Individuals with β-thalassemia develop progressive systemic iron overload, resulting in high morbidity and mortality. These complications are caused by labile plasma iron, which is taken up by ...

Incorporating structural constraints into pharmacokinetic studies of iron sucrose formulations. Results from assays conducted independently of one another can produce findings that are incompatible ...

A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people with low levels and very high levels of a commonly measured laboratory ...

What Is a TIBC Blood Test? A total iron-binding capacity test is a blood test that tells you how much iron is binding to the transferrin in your blood, which tells you how well iron is functioning in ...

The blood brain barrier (BBB) exists to protect the brain from pathogens and other toxins but makes central nervous system (CNS) diseases hard to treat with conventional drugs. For example, many ...

Low iron saturation occurs when the amount of iron in the blood decreases below the recommended range. Measuring transferrin is one way to determine iron saturation. Iron saturation refers to the ...

Clinical utility of tumor next-generational sequencing (NGS) panel testing to inform treatment decisions for patients with advanced solid tumors. This is an ASCO Meeting Abstract from the 2022 ASCO ...

Medizinische Universitätsklinik Freiburg, Abteilung Rehabilitative und Präventive Sportmedizin, Hugstetter Str 55, 79106 Freiburg, Germany Correspondence to: Dr Schumacher, Abtlg RP Sportmedizin, ...

For decades scientists have sought a way to sneak large drugs across the blood-brain barrier. These efforts received a boost in 2011, when researchers led by Ryan Watts at Genentech, South San ...

Over the last three decades, scientists have devised molecular shuttles that slip enzymes, antibodies, and other molecules into the central nervous system (CNS) by attaching them to the transferrin ...