Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.

Oncotarget recently published "Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis" by Kim, et al. which reported that the authors show that CADD522 inhibits ...

Recently, a research team led by Professor Hongzhe SUN from the Department of Chemistry, Faculty of Science, The University of Hong Kong, has published a paper in Nature Communications. The ...

A phase II multicenter study of the cyclin-dependent kinase inhibitor indisulam in patients with progressive inoperable and/or metastatic renal cell carcinoma (RCC) No significant financial ...

In a recent study published in Nature, researchers from the United States of America investigated how cells separate competing metabolic pathways within mitochondria, namely oxidative phosphorylation ...